Management Team
Robin Bhattacherjee

Robin Bhattacherjee, Chief Executive Officer

Robin Bhattacherjee BSc (Hons) joined Actimed Therapeutics as CEO in August 2019. Robin was previously with Actelion from 2009 and was the General Manager for the UK and Ireland Affiliate and a member of the European Management Team.
 
Robin served on the ABPI Board of Management from 2011 – 2017 as one of the elected Small Companies Group representatives, with a particular interest in medicines that come under specialised commissioning. Prior to Actelion, Robin was the General Manager for CV Therapeutics Europe (CVT) from 2004 to mid-2009, prior to the acquisition of the Company by Gilead. Responsibilities included delivering the European licencing and pre-marketing objectives for the product portfolio and the build and management of European affiliates. He also played a major role in successful European business development activities. Robin joined CVT from Sanofi-Synthélabo UK, where he was Head of Marketing and he also sat on the Irbesartan Global Strategy Team.
 
From 1986 to 2002, Robin held a variety of positions at Bayer including Marketing Manager and National Sales Manager in the UK and he was a Director in Bayer’s Global Strategic Marketing Group. During his career, Robin has been involved in several product launches both in the UK and Europe. Robin grew up in the North West of England and has an honours degree in Biological Sciences gained at University of London.

Fabio Dorigotti

Fabio Dorigotti, Chief Medical Officer

Fabio Dorigotti  MD brings over 25 years of pharmaceutical industry experience spanning the full breadth of the clinical development process. Prior to joining Actimed, Dr Dorigotti was CMO of Swiss biopharmaceutical company Quercis Pharma. During his career, Dr Dorigotti has held inhouse roles of Head of Global Medical Affairs for CSL Vifor and Medical Affairs Director at AstraZeneca, and as Chief Strategy Officer and President of Global Clinical for Worldwide Clinical Trials, a full-service global contract research organization (CRO). He has a strong track record of successful clinical development and product marketing approvals, alongside a deep understanding of FDA, EMA and other regulatory agencies.  

Shaun Claydon

Shaun Claydon, Chief Financial Officer

Shaun Claydon brings over 16 years of board-level experience and a proven finance track record, particularly within the biotechnology sector. A qualified Chartered Accountant, his significant industry experience includes serving as CFO of Creabilis, where he played a key role in its $150 million sale to Sienna Biopharmaceuticals. Shaun has also held senior roles as CFO and COO at Orteq Sports Medicine, and as CFO of Destiny Pharma, a clinical-stage biotech focused on novel anti-infectives. Earlier in his career, he worked in financial consultancy and corporate finance at PwC, Evolution Beeson Gregory (now Investec), and HSBC Investment Banking. 

Elaine Morten

Elaine Morten, Head of Regulatory Affairs and Technical Development

Elaine Morten, PhD began working with Actimed in 2017 as a consultant before joining the Company in 2022. Elaine brings over 25 years of global drug development experience to Actimed predominantly obtained in small to mid-size organisations.  Elaine has a track record of taking products through development to marketing authorisation and beyond and has diverse therapeutic and territorial experience.  Prior to joining Actimed, Elaine was an independent consultant to the Pharmaceutical Industry and before this, she was Vice President of Regulatory Affairs and Head of Pharmacovigilance at The Medicines Company. Elaine has also worked for British Biotech as Head of Regulatory Affairs and Shire Pharmaceuticals as Regulatory Affairs Manager. 

Louise Bosworth

Louise Bosworth, Head of Clinical Operations

Louise Bosworth is the Head of Clinical Operations and Quality for Actimed, responsible for leading the Clinical Operations Strategy and delivering the Clinical Development Programme. With over 25 years of Clinical Development and Quality experience in the pharmaceutical industry, Louise joined Actimed in September 2021. Louise has held senior positions at large pharma companies including Eli Lilly & Company and Amgen as well as smaller biopharma companies, GW Pharma and Orphalan. Louise has also worked for the leading Clinical Research Organisation IQVIA. Louise’s extensive quality experience includes establishing Quality Management Systems, leading both local and international inspection readiness programs as well as regulatory inspections. Her broad therapeutic and management responsibilities incorporate Clinical and Quality expertise across the industry including fields of oncology and rare diseases products. 

Hugh Jackson

Hugh Jackson, Finance Director and Company Secretary

Hugh Jackson is a finance professional with more than 30 years’ experience. He specializes in providing SMEs with business growth and strategic planning advice together with management reporting and compliance assurance. Over this period, working with owner-managers, business angels and venture capitalists, Hugh has assisted in completing more than 20 successful exit transactions, together with several fundraising transactions, including a Nasdaq flotation and several SEIS / EIS fundraises.

Hugh studied at Exeter University and qualified as a chartered accountant with Price Waterhouse in 1988. He established his own accountancy practice, Jacksons, in 1990.

Feb 6, 2025
Actimed Therapeutics Expands Intellectual Property Portfolio
  • Two new composition of matter patents granted in the US and Europe
  • Patents provide protection relating to lead compound S-pindolol benzoate (ACM-001.1), significantly strengthening company’s intellectual property portfolio

 

London, UK – 6 February 2025. Actimed Therapeutics, a UK based clinical stage speciality pharmaceutical company focused on bringing innovation to the treatment of cancer cachexia and other muscle wasting disorders, announces today that it has received new patent grants from the United States Patent and Trademark Office (USPTO) and the European Patent Office (EPO). 

Both patents provide protection relating to ACM-001.1 (S-pindolol benzoate), an anti-catabolic and pro-anabolic transforming agent (ACTA) with a multifunctional effect on key pharmacological targets relevant for cancer cachexia and other muscle wasting disorders.

  • European Patent EP 4132909 B covers a pharmaceutically acceptable salt of: (i) S-pindolol; and (ii) benzoic acid.   
  • US Patent US 12,109,192 B covers the two preferred crystalline forms of S-pindolol benzoate.  

 

  • Robin Bhattacherjee, Actimed CEO, commented: “I am delighted to confirm the grant of these two key patents relating to ACM001.1, which provide robust intellectual property supporting our lead asset. This is crucial as we focus on advancing ACM001.1 into late-stage clinical development for cancer cachexia. The impact of cancer cachexia on patients and the urgent need for new treatments has become increasingly apparent, and we continue to press ahead with our plans to bring our potential new therapy to the many cancer patients suffering from this devastating condition.”

 

About Actimed Therapeutics  

Actimed Therapeutics is a clinical stage speciality pharmaceutical company focused on bringing innovation to the treatment of muscle wasting disorders to transform the care of an underserved and vulnerable patient population. 

The lead area of focus for Actimed is specifically in cachexia. Cachexia is a wasting disease that is associated with cancer and other serious chronic illnesses and with significant morbidity and mortality. A significant number of cancer patients suffer from cachexia1 and it is estimated that cachexia is responsible for up to 20% of all cancer deaths2. A recent meta-analysis demonstrated that cachexia was associated with an 82% higher relative risk of mortality in patients with NSCLC versus no cachexia3.

Despite its prevalence and devastating clinical effects, there is no globally approved drug for the treatment or prevention of cancer-related cachexia.  

Actimed is currently preparing for further clinical studies of its lead product ACM-001.1. (S-pindolol benzoate) which is an anti-catabolic and pro-anabolic transforming agent (ACTA) targeting multiple pathways that drive cancer cachexia. Previous studies with S-pindolol have generated promising Phase 2a proof of concept data in cachexia patients and Actimed has conducted a pharmacokinetic and pharmacodynamic (PK/PD) study of S-pindolol benzoate to characterise this new form.  ACM001.1 has achieved Investigational New Drug (IND) status from FDA.

Actimed also owns the global rights to its second asset, S-oxprenolol (ACM-002), which is being developed by the Company for the muscle wasting seen in amyotrophic lateral sclerosis (ALS) where loss of body mass and muscle wasting may impact survival4. Actimed was granted US Orphan Drug Designation to S-oxprenolol for the treatment of ALS in 2024. Actimed has licensed the global rights to develop and commercialise S-oxprenolol for cancer cachexia and any other indications outside of ALS to US company Faraday Pharmaceuticals.

 

FOR MORE INFORMATION

Actimed Therapeutics

MEDiSTRAVA 
Frazer Hall, Erica Hollingsworth
Tel: +44 (0)203 928 6900
Email: actimed@medistrava.com

 

1 Anker M et al., J. Cachexia, Sarcopenia and Muscle; 2019: 10: 22 – 24
2 Argilés JM et al, Nat Rev Cancer 2014; 14:754-62
3 Bonomi P. et al. The mortality burden of cachexia in patients with non-small-cell lung cancer: A meta-analysis; International Conference of Sarcopenia, Cachexia and Wasting Disorders, June 17 – 18 2023, Stockholm, abstract 2-18, page 139
4 Wolf J et al., PMID 28184974 DOI: 10.1007/s00115-117-0293