Mode of action
• β-1receptor antagonism that blocks catabolism
• Increased anabolism, through partial β2 receptor agonism. β-2 agonist effect that can grow muscle
• 5-HT1A effects that can stimulate appetite and thereby improve overall patients outcomes as well as improving fatigue.
Anticatabolic and pro-anabolic pharmacological effects highly advantaged candidate for development in cancer cachexia.
Cachexia therapy / Unmet / Medical need / Cancer / Drug development / Patient's lives / Innovation